Breast Cancer Research. Ageing as Predisposing Factor

Inhaltsverzeichnis (Table of Contents)

• Abstract
• Introduction
• Literature Review Related to the Topic
  • Lifetime Risks and Incidence of Breast Cancer by Age and Molecular Subtype
  • Genetics and Breast Cancer Risks with Age
  • Prognosis
  • The length of menstrual cycle and the Age at menarche
  • Age at Menopause
  • microRNAs and breast cancer
• Methodology
  • Case 1: A Meta-analysis and Systematic Review of the Risk Factors for Breast Cancer for Women of between 40 and 60 Years
  • Case 2: A Vivid Analysis of the Progesterone Receptor Negative, Estrogen Receptor Negative, and HER2 Negative Invasive Breast Cancers or rather the Triple Negative Phenotypes
• Results
• Discussion
• Limitations
• Conclusion
• Recommendations

Zielsetzung und Themenschwerpunkte (Objectives and Key Themes)

This research aims to investigate whether age is a predisposing factor for breast cancer. It explores the relationship between age and breast cancer incidence, diagnosis, treatment, and management, examining the influence of age on the biology of the disease. Additionally, the study delves into the potential of emerging technologies and tests, like microRNAs, in improving breast cancer identification and treatment.

• Age as a predisposing factor for breast cancer
• Influence of age on breast cancer incidence, diagnosis, and treatment
• Biology of breast cancer and its age-dependent characteristics
• Role of hormone receptors and genetic factors in breast cancer development
• Emerging technologies and tests for breast cancer identification and treatment

Zusammenfassung der Kapitel (Chapter Summaries)

The introduction provides an overview of breast cancer, its prevalence, and the significance of age as a risk factor. The literature review extensively discusses the lifetime risks and incidence of breast cancer across different age groups, highlighting the impact of age on various molecular subtypes. It also explores the role of genetics, prognosis, menstrual cycle, menopause, and microRNAs in relation to breast cancer and age. The methodology section outlines the research approach, including a meta-analysis and systematic review of risk factors for breast cancer in women between 40 and 60 years and a detailed analysis of triple-negative breast cancer phenotypes. The results and discussion sections present findings and interpretations, while the limitations acknowledge the study's constraints.

Schlüsselwörter (Keywords)

The key terms and concepts of the work include breast cancer, age, predisposing factors, incidence, diagnosis, treatment, management, hormone receptors, genetics, microRNAs, triple-negative breast cancer, molecular subtypes, and emerging technologies.