Doktorarbeit / Dissertation, 2014
168 Seiten, Note: A
CHAPTER 1 INTRODUCTION
1.1 ECG and its Importance
1.2 ECG Lead System
1.3 Need for ECG Monitoring System
1.4 Literature Survey
1.5 Methodology
1.6 Organization of thesis
CHAPTER 2 ECG DATA ACQUISITION SYSTEM AND HEART RATE MEASUREMENT
2.1 ECG System Requirements
2.1.1 Data Acquisition Unit
2.1.2 Data Processing Unit
2.1.3 Data Communication Unit
2.1.4 Data Analysis Unit
2.2 ECG Signal Data Acquisition
2.2.1 Electrodes used for ECG Signal Pickup
2.2.1.1 Surface Electrodes
2.2.1.2 Adhesive Electrodes
2.3 Instrumentation Amplifier
2.3.1 Requirements of Instrumentation Amplifier
2.3.2 AD620 Instrumentation Amplifier
2.4 Simple ECG Acquisition System
2.4.1 Filters Used in ECG System
2.4.1.1 Low Pass Filter (LPF)
2.4.1.2 High Pass Filter (HPF)
2.4.1.3 Notch Filter
2.5 Data Processing
2.5.1 ADC0804 Analog to Digital Converter
2.5.2 Serial communication using microcontroller 89C51
2.6 Power Supply
2.7 Data Communication Unit
2.7.1 Communication of Data HyperTerminal
2.7.1.1 Steps involved to setup a new connection using window interface
2.7.1.2 Steps involved in saving incoming data to a text file
2.8 Realization of Sigma Delta ADC using Simulink
2.9 Heart Rate Measurement using LABVIEW
2.9.1 Implementation of LABVIEW for ECG Instrumentation and Analysis
2.9.2 Data Acquisition Module
2.9.3 Amplification Module
2.9.4 Filtering module
2.9.5 QRS Detection and Heart Rate Calculation
CHAPTER 3 ECG COMPRESSION TECHNIQUES
3.1 Performance Evaluation of compression
3.1.1 Compression Measurement
3.1.2 Distortion Measurement
3.2 Data Compression
3.2.1 Direct Data Compression
3.2.2 Transformation Methods
3.3 Compression techniques used in the Proposed Work
3.3.1 Amplitude Zone Time Epoch Coding (AZTEC) Algorithm
3.3.1.1 Line Detection (Horizontal Mode) Procedure
3.3.1.2 Line Processing (Slope Mode) Procedure
3.3.2 Turning Point (TP) Algorithm
3.3.3 Coordinate Reduction Time Encoding System (CORTES) Algorithm
3.3.4 Discrete Cosine Transform (DCT) Algorithm
3.3.5 Fast Fourier Transform (FFT) Algorithm
3.4 Comparison of various Compression Techniques
3.4.1 Conclusions
CHAPTER 4 LINEAR VECTOR QUANTIZATION FOR ECG SIGNAL CLASSIFICATION
4.1 Feature Extraction
4.1.1 QRS Detection
4.1.2 R-R Interval Calculation
4.1.3 ST Segment Measurement
4.1.4 Heart Rate Determination
4.2 Artificial Neural Network
4.2.1 Training the Neural Network
4.2.2 Supervised Training for Neural Network
4.3 Linear Vector Quantization (LVQ)
4.3.1 ECG Signal Data Set
4.3.2 Training Algorithm for ECG Signal Classification
4.3.3 Application of the ECG Signal Analysis using LVQ Method
4.3.4 Classifier Performance
CHAPTER 5 RESULTS OF ECG ACQUISITION, COMPRESSION AND ANALYSIS
5.1 Hardware Implementation for Data Acquisition
5.2 Results of the ECG Compression
5.3 Results of Linear Vector Quantization (LVQ) for ECG Signal Analysis
CHAPTER 6 DISCUSSION ON RESULTS
CHAPTER 7 CONCLUSION AND FUTURE WORK
The primary research objective is to develop a portable, wireless ECG monitoring system that enables real-time acquisition and classification of cardiac arrhythmias. The study focuses on reducing memory storage and communication bandwidth requirements through efficient signal compression techniques while simultaneously improving diagnostic accuracy using advanced machine learning algorithms.
1.1 ECG AND ITS IMPORTANCE
The heart is a muscular organ responsible for pumping blood through the blood vessels by repeated and rhythmic contractions in human beings. The average human heart, beating at 72 beats per minute, will beat approximately 2.5 billion times during a lifetime (about 66 years). It weighs on average 250g to 300g in females and 300g to 350 g in males.
The function of the right side of the heart is to collect de-oxygenated blood, in the right atrium, from the body (via superior and inferior vena cava) and pump via the right ventricle, into the lungs (pulmonary circulation) through pulmonary valve so that carbon dioxide is exchanged with oxygen. This happens through the passive process of diffusion. The left side collects oxygenated blood from the lungs into the left atrium. From the left atrium the blood moves to the left ventricle which pumps it out to the body (via the aorta). On both sides, the ventricles are thicker and stronger than the atria [2].
The Sino Atrial (SA) node is the natural pacemaker that regulates the cardiac function. The SA node is located at the upper portion of the Right Atrium (RA) and is a collection of specialized electrical cells. SA node generates the pulses at regular intervals that travel through a specialized electrical pathway and stimulates the muscle wall of the four chambers of the heart to contract in a certain sequence or pattern. The upper chambers or atria are first stimulated. This is followed by a slight delay to allow the two atria to empty. Finally, the two ventricles are electrically stimulated to expel the blood into the arteries.
As the SA node fires, each electrical impulse travels through the right and left atria. This electrical activity causes the two upper chambers of the heart to contract. This electrical activity can be recorded from the surface of the body as a "P wave" on the Electro Cardio Gram recording (ECG). The electrical impulse then moves to an area known as the Atria-Ventricular (AV) node.
CHAPTER 1 INTRODUCTION: This chapter introduces the prevalence of heart disease, the importance of continuous ECG monitoring, and outlines the thesis structure.
CHAPTER 2 ECG DATA ACQUISITION SYSTEM AND HEART RATE MEASUREMENT: Covers the hardware design, including instrumentation amplifiers, filter circuits, and the implementation of ZigBee and LabVIEW for data acquisition.
CHAPTER 3 ECG COMPRESSION TECHNIQUES: Details various compression algorithms like AZTEC, CORTES, and DCT, evaluating their performance based on compression ratios and signal reconstruction quality.
CHAPTER 4 LINEAR VECTOR QUANTIZATION FOR ECG SIGNAL CLASSIFICATION: Discusses feature extraction methods and the application of Artificial Neural Networks and LVQ to classify ECG signals into specific cardiac conditions.
CHAPTER 5 RESULTS OF ECG ACQUISITION, COMPRESSION AND ANALYSIS: Presents the experimental data, including hardware performance results and comparative results for different compression and classification algorithms.
CHAPTER 6 DISCUSSION ON RESULTS: Provides an analytical review of the implemented hardware and algorithms, comparing the research findings with existing literature and highlighting system advantages.
CHAPTER 7 CONCLUSION AND FUTURE WORK: Summarizes the study’s findings and suggests future improvements, such as the use of DSP controllers and multichannel analysis.
ECG, Arrhythmias, Data Compression, Discrete Cosine Transform, Linear Vector Quantization, Wireless Monitoring, ZigBee, LabVIEW, QRS Detection, Heart Rate, Signal Acquisition, Biomedical Instrumentation, Neural Networks, Telemedicine, Cardiac Abnormalities
The research focuses on the design and implementation of a portable, wireless ECG monitoring system that enables real-time cardiac abnormality detection, alongside efficient data compression techniques to manage storage requirements.
The study integrates biomedical engineering, digital signal processing, wireless sensor networks (ZigBee), and machine learning/neural networks for medical diagnosis.
The primary goal is to build a wearable, continuous monitoring system capable of automatically classifying cardiac arrhythmias in real-time, thereby reducing the burden on clinicians and improving patient turnaround times.
The system uses instrumentation amplifiers, analog-to-digital converters (ADC), filtering stages, and advanced algorithms such as the Discrete Cosine Transform (DCT) for compression and Linear Vector Quantization (LVQ) for pattern classification.
The classification is performed using a Linear Vector Quantization (LVQ) neural network trained on features like R-R intervals, QRS duration, heart rate, and ST segment slopes derived from the ECG data.
The study evaluated AZTEC, Turning Point (TP), CORTES, FFT, and Discrete Cosine Transform (DCT) methods to compare their effectiveness in reducing data size.
The system utilizes a combination of hardware-based filtering (low-pass, high-pass, and notch filters) and adaptive signal processing techniques in the software domain to ensure signal integrity.
The proposed DCT-based technique achieved a significant compression ratio (CR) between 82% and 90.43% with a low Percent Root Mean Difference (PRD) of 0.93 to 7.9, outperforming several other literature-based approaches.
The implemented LVQ neural network achieved an overall accuracy of 95.5% in identifying four distinct classes of cardiac abnormalities: Tachycardia, Bradycardia, Premature Ventricular Contraction, and Myocardial Infarction.
Future work could involve integrating DSP controllers directly into the data acquisition hardware to enable on-device compression, as well as evolving the system from a single-channel to a multi-channel configuration for broader diagnostic insights.
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