Analytical Method Development and Stability Studies of Carvedilol

Inhaltsverzeichnis (Table of Contents)

• CHAPTER: 1 INTRODUCTION
  • 1. Introduction
• CHAPTER: 2 LITERATURE REVIEW
  • 2.1 Literature review
• CHAPTER: 3 PROLOGUES TO THE EXPERIMENTAL WORK
  • 3.1 Scope and objectives
  • 3.2 Plan of work
  • 3.3 Requirements
• CHAPTER: 4 EXPERIMENTAL
  • 4.1 UV-VIS method development
  • 4.2 RP-HPLC method development
  • 4.3 Forced degradation Studies
• CHAPTER: 5 RESULTS AND DISCUSSION
  • 5.1 UV-VIS Analysis
  • 5.2 RP-HPLC Analysis
  • 5.3 Forced degradation studies
• CHAPTER: 6 CONCLUSIONS
  • 6.1 Conclusion
• CHAPTER: 7 REFERENCES
  • 7.1 References

Zielsetzung und Themenschwerpunkte (Objectives and Key Themes)

This thesis focuses on the development and validation of analytical methods for the drug carvedilol, followed by a comprehensive stability study using forced degradation techniques. The primary objective is to establish reliable and accurate analytical methods for the quantification of carvedilol in various pharmaceutical formulations.

• Analytical Method Development and Validation
• Stability Studies of Carvedilol
• Forced Degradation Techniques
• UV-Vis Spectrophotometry
• RP-HPLC Analysis

Zusammenfassung der Kapitel (Chapter Summaries)

Chapter 1 provides an introduction to spectrophotometric methods, highlighting their importance in pharmaceutical analysis. The chapter delves into the principles of UV-Vis spectroscopy and its applications in drug analysis. Chapter 2 presents a comprehensive literature review on the analytical methodologies and stability studies of carvedilol, summarizing existing research and providing context for the current work. Chapter 3 outlines the scope, objectives, plan, and requirements of the experimental work. Chapter 4 details the experimental methodologies employed for developing and validating UV-Vis and RP-HPLC methods for carvedilol analysis, along with the forced degradation studies performed to assess the drug's stability. Chapter 5 presents and discusses the results obtained from the experimental work, analyzing the performance of the developed methods and the stability of carvedilol under various conditions. Chapter 6 concludes the thesis by summarizing the key findings and highlighting the significance of the research.

Schlüsselwörter (Keywords)

Carvedilol, analytical method development, UV-Vis spectrophotometry, RP-HPLC, stability studies, forced degradation, pharmaceutical analysis, drug quantification, analytical validation.