Doktorarbeit / Dissertation, 2007
94 Seiten, Note: A (Gold Medalist)
02. Prologue
03. Chapter 1 (Conceptual study of the principle)
04. Chapter 2 (Disease Review)
05. Chapter 3 (Drug Review)
06. Clinical Study
07. Discussion
08. Conclusion
09. Summary
10. Bibliography
11. Research Proforma
This work aims to evaluate the clinical application of the Ayurvedic principle "Poorvah purvo ati vriddhatvat vardhayeddhi param param" (the principle of tissue interconversion) in the management of Rakta-Kshaya (Anaemia). The study seeks to bridge the gap between classical Ayurvedic theoretical frameworks and contemporary clinical practice by assessing the efficacy of Shatavari Siddha Ksheera on patients suffering from Rakta-Kshaya.
CONCEPTUAL STUDY
The fundamental principles of the study of the disease are mentioned in Ayurveda classics including the Sushruta Samhita. The disease as per the Ayurveda philosophy is termed as the imbalance of the three vital humors called as the vata, pitta and kapha. They are termed as dosha in Ayurveda parlance. The dosha is the strongest and independent unit of Ayurveda physiology and pathology. The Ayurveda has propagated the principle of the harmony of the microcosm and the macrocosm in the form of the lok-purusha samya siddhanta (The principle of the similarity of the universe and the living being).
The classics of Ayurveda elaborate on the diseases in the form of increase or decrease of the dosha-dhatu. The Sootra Sthana of Sushruta Samhita is the unique treasure of knowledge elaborating on all the fundamentals of Ayurveda. Though all the forty six chapters of the Sootra Sthana of Sushruta Samhita are unique in their subject and content having wide range of applications to every branch of Ayurveda this work is confined to the study of the Rakta Kshaya (Anaemia) and its management based on the principle of the inter-relation of tissues elaborated in the chapter15th of Sootra Sthana of Sushruta Samhita namely the“Dosha- dhatu- mala Kshaya Vriddhi Vijnaneeya Adhyaya”.
The homeostasis of the body is the equilibrium of these Dosha- dhatu- Mala while theunhealthy state is the disturbance of this equilibrium which is manifested either as Kshaya (diminution) or Vriddhi (increase). This Kshaya and Vriddhi of the Dosha Dhatu Mala is the crux of the chapter fifteen of the Sootra Sthana of the Sushruta Samhita namely “Dosha-dhatu-Mala-kshaya-Vriddhi Vijnaneeya Adhyaya”.
Chapter 1 (Conceptual study of the principle): This chapter establishes the theoretical foundation by exploring the inter-relation of tissues through the principle "Poorvah purvo ati vriddhatvat vardhayeddhi param param".
Chapter 2 (Disease Review): This section provides an in-depth Ayurvedic analysis of Rakta-Kshaya (Anaemia), covering its etiology, pathogenesis, and clinical symptoms.
Chapter 3 (Drug Review): This chapter focuses on the pharmacological and classical review of Shatavari as a primary therapeutic agent for Rasa and Rakta replenishment.
Clinical Study: This section details the methodology and clinical trials conducted on patients to test the efficacy of the chosen pharmacological intervention.
Discussion: This segment correlates the theoretical findings with clinical observations, providing a logical reasoning for the therapeutic outcomes.
Conclusion: This final section synthesizes the results, confirming the practical application of the researched Ayurvedic principle in modern clinical settings.
Ayurveda, Rakta-Kshaya, Anaemia, Shatavari, Dhatu-Poshana, Poorvah purvo ati vriddhatvat, Sootra Sthana, Sushruta Samhita, Tissue Nourishment, Clinical Study, Rasa Dhatu, Pathogenesis, Dosha, Dhatavagni, Kayachikitsa
The research focuses on validating the Ayurvedic principle of tissue interconversion to treat Anaemia (Rakta-Kshaya) by nourishing the Dhatus.
The central themes include the theoretical framework of Dhatu Poshana (tissue nourishment), the pathogenesis of Rakta-Kshaya, and the therapeutic evaluation of Shatavari.
The core question is whether the principle of "Poorvah purvo ati vriddhatvat vardhayeddhi param param" can effectively manage Rakta-Kshaya in clinical practice.
The study utilizes a literary research method for the conceptual framework and a randomized clinical trial for the applied study of the therapeutic agent.
The main body covers a comprehensive review of Ayurvedic literature, the selection of test drugs, and the systematic clinical observation of 26 patients.
Key terms include Ayurvedic Principles, Rakta-Kshaya, Dhatu-Poshana, and Clinical Validation.
Shatavari is used as a Rasayana (rejuvenative) and Rasa-vardhaka (plasma-increasing) drug to assess its secondary effect on nourishing the Rakta Dhatu.
Yes, the study concludes that replenishing Rasa Dhatu is a crucial prerequisite for the proper nourishment and stabilization of Rakta Dhatu.
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