Numerical Flow Simulation in FDA's "Critical Path" benchmark blood pump

Inhaltsverzeichnis (Table of Contents)

• Introduction
  • Ventricular Assist Device
  • History of VADs
  • Operating Conditions for VAD
  • Role of Computational Fluid Dynamics
• Literature Review
  • Blood
    • Red Blood Cells
  • Blood Rheology
  • Blood damage
  • Numerical Hemolysis Prediction
• Description of Turbulence Modeling
  • RANS/URANS
    • Shear Stress Transport model
• Experimental Study
• Pre-Processing
  • Structure of FDA blood pump
  • Mesh Information
    • Mesh Overview
    • Mesh Generation
• Computation
• Results and Discussion
  • Convergence
  • Pressure Head
  • Flow Field
  • Wall Shear Stress and Hemolysis Comparison

Zielsetzung und Themenschwerpunkte (Objectives and Key Themes)

This master thesis aims to analyze the flow fields in the FDA's "Critical Path" benchmark blood pump, contributing to the advancement of Computational Fluid Dynamics (CFD) in biomedical applications. The work focuses on validating the efficiency of computer simulations for the development and optimization of Ventricular Assist Devices (VADs), specifically blood pumps.

• CFD in Biomedical Applications
• Blood Pump Design and Optimization
• Hemolysis Prediction
• Computational Modeling of Blood Flow
• Validation of CFD Simulations

Zusammenfassung der Kapitel (Chapter Summaries)

The thesis begins with an introduction to VADs, their history, and the role of CFD in their development. Chapter 2 provides a literature review on blood, blood rheology, blood damage, and numerical hemolysis prediction. Chapter 3 details the turbulence modeling used, specifically the RANS/URANS approach and the Shear Stress Transport model. The pre-processing stage, including the structure of the FDA blood pump and the mesh generation process, is outlined in Chapter 5. Chapter 6 discusses the computational methods used. Finally, Chapter 7 presents the results and discussion of the simulation, including convergence, pressure head, flow field analysis, and hemolysis prediction.

Schlüsselwörter (Keywords)

The key terms and concepts explored in this thesis include Computational Fluid Dynamics (CFD), Ventricular Assist Device (VAD), blood pump, block-structured hexahedral mesh, URANS, k-w SST, hemolysis, Power Law, stress-based model, and Eulerian approach.