Masterarbeit, 2019
78 Seiten, Note: 4
This research thesis aims to investigate the antibacterial activity of four plant species commonly used in traditional medicine practices in the South Omo Zone of Southern Ethiopia. The study explores the potential of these plants to combat antimicrobial resistance, a growing global health concern.
The thesis begins by outlining the background of the study, highlighting the significance of antimicrobial resistance and the potential of plant-based solutions. Chapter Two provides a comprehensive review of existing literature related to antimicrobial resistance, plant-based antimicrobial studies in Ethiopia, and ethnobotanical data on medicinal plants found in the Omo Valley. This chapter also focuses on the four specific plants selected for the study, reviewing their traditional uses and known properties. Chapter Three outlines the general and specific objectives of the research, which aim to determine the antibacterial activity of the selected plants against specific bacterial strains, both from standard cultures and clinical isolates. Chapter Four details the materials and methods used in the study, including the description of the study area, the selection and collection of plant materials, the preparation of plant extracts, the bacterial strains used, and the methodologies employed for the antibacterial assays. Chapter Five presents the results of the study, including the primary antibacterial screening of all four plant species against standard bacterial strains and the extended screening of two promising species against multidrug resistant (MDR) clinical isolates. This chapter also includes the determination of the minimum inhibitory concentration (MIC) of the most effective plant extract against both standard and MDR bacterial strains. Chapter Six provides an in-depth discussion of the results, analyzing the findings in the context of existing literature and highlighting the significance of the study's conclusions.
The research focuses on traditional medicine, plant-based antimicrobials, antimicrobial resistance, South Omo Zone, Ethiopia, antibacterial activity, minimum inhibitory concentration, ethnobotany, medicinal plants, and clinical isolates.
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MSc Sintayehu Gobezie
This is the part of ongoing activity devoted to the traditional healers and ritual leaders in the lower Omo valley, where I am working. Thanks to the people of Omo valley and organization for natural medicine and nutrition at lower Omo valley.
am 27.1.2021